Trisomie 21 (Literally, a 21st chromosome trisomy, also knows as Down Syndrome), is a group by Philippe Lomprez and Hervé Lomprez, two brothers from Lille, France. Hervé is a Professor of Sounds Technology. Their early music is considered French coldwave (an early cousin of "darkwave"), while their later music electro-pop. Throughout the 80's and 90's, T21 was signed to PIAS Records and their most popular song was "The Last Song".

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