The Axe Murder Boyz are from Denver. They are originally from the West Denver area of the city. James and Mike Garcia are brothers of Mexican-American and Spanish descent. Axe Murder Boyz released a series of underground local releases on their own label, Axe Recordings, before creating Canonize Productions and releasing their debut studio album, The Unforgiven Forest, in 2004.
In 2005, AMB won the Underground Psychos contest that Psychopathic Records was holding.