Melvin "Lil' Son" Jackson (August 16, 1915, Tyler, Texas - May 30, 1976, Dallas) was an American blues guitarist. Jackson's mother played gospel guitar, and he played early on in a gospel group called the Blue Eagle Four. He trained to be a mechanic and did a stint in the Army during World War II, then decided to pursue a career in blues music. He was a contemporary of Lightnin' Hopkins.
He recorded a demo and sent it to Bill Quinn, the owner of Gold Star Records, in 1946.