He was a choirboy in his youth at Lambert's cathedral in Liège. As early as 1562 he sang in the Imperial Chapel in Vienna. In 1569 he was master at Melk Abbey. In the years 1570 to 1571 we find him at the court of Archduchess Anna Maria for her wedding to the King of Spain Philip II. From 1577 to 1582 Sayve served the Archduke Charles in Graz. From 1583 he was Kapellmeister at the court of the Archduke Matthias.